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Under the care of a series of distinguished conservators such as Richard Owen, William Flower and Arthur Keith, precious collections from John Hunter, developed into one of the largest collections of its kind anywhere in the world. Each conservator added to the collection, reflecting their own academic interests and broader changes in the direction of scientific research. By the end of the 19th century the museum contained nearly 65,000 specimens covering anatomy and pathology; zoology; palaeontology; archaeology and anthropology.
Today the college has been rebuilt and four new museums were created. Specimans used for teaching and research were transferred to the Wellcome Museums of Anatomy and Pathology. The Odontological Collection was housed in a separate museum, and in 1963 a new Hunterian Museum was opened.