The world famous Nobel Prize in medicine winning Rita Levi-Montalcini has finally passed away in Rome at the age of 103. She lived a long and eventful life devoted to science and had worked well into her later years stating that even at 100 her mind had grown sharper than it was at 20 due to experience.

ROME (AP) _ Rita Levi-Montalcini, a biologist who conducted underground research in defiance of Fascist persecution and went on to win a Nobel Prize for helping unlock the mysteries of the cell, died at her home in Rome on Sunday. She was 103 and had worked well into her final years.

Rome Mayor Gianni Alemanno, who announced her death in a statement, called it a great loss “for all of humanity.” He praised her as someone who represented “civic conscience, culture and the spirit of research of our time.”

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