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Santiago in 24 Hours: A Fast-Track Guide to the Chilean Capital for Curious Travelers

Santiago, Chile credit: Chalo Gallardo/Unsplash

Set against a dramatic backdrop of the Andean mountain range, Chile’s capital city is a dynamic metropolis where sleek high-rises share space with colonial architecture and green parks thread between neighborhoods. Whether passing through on a layover or pressing pause before venturing to nearby ski resorts or lunar-like desert landscapes in the far north, Santiago packs a cultural punch that’s surprisingly accessible in just one day and makes a rewarding stop on any Chilean or South American itinerary.

Where to Stay: Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

Set in the upscale Las Condes district—known for its leafy boulevards and proximity to Santiago’s financial and cultural hubs—Mandarin Oriental, Santiago makes a serene yet connected base. As the brand’s first venture in South America, the hotel has established itself as a contemporary landmark: its distinctive mirrored façade catches the eye and beautifully reflects the snow-capped Andes. Lush gardens and pool add a resort-like ambiance, making it easy to unwind after a day exploring. 

Mandarin Oriental, Santiago provides a resort-style stay in the heart of the city

The hotel’s new rooftop garden—part of its ongoing sustainability initiatives—cultivates over 45 varieties of herbs, vegetables, and greens, with chef-led tours available to guests. It also houses a working apiary that produces small-batch honey, featured in select dishes and desserts across its dining venues: the elegant Atrium Lobby Lounge, Italian favorite Senso, and the Japanese-inspired Matsuri. To ease arrival, the hotel offers chauffeur service from Arturo Merino Benítez International Airport; once checked in Santiago’s cultural landmarks and culinary hotspots are a short walk or ride away.

One of the new Panoramic Suites at Mandarin Oriental, Santiago

Following a comprehensive multi-phase renovation, two stunning Panoramic Suites are new jewels in the Mandarin Oriental's crown—lofty and light-filled top-floor residences with floor-to-ceiling windows that enjoy uninterrupted views over Santiago's skyline and golf course. Elegantly appointed, they feature custom furnishings and exquisite bathrooms with soaking tubs, plus amenities such as 24-hour in-room dining. Equally as refined are the Executive Rooms with their smart split-level layouts and exclusive access to the 16th-floor Club Lounge, where perks include breakfast, all-day refreshments, evening cocktails and curated wine tastings

What to See in Santiago

Parque Almagro, Santiago credit: Luis Chávez/Unsplash

A single day in Santiago calls for streamlined choices and purposeful exploration. Mornings are a great time to take the funicular up to the summit of Cerro San Cristóbal, Santiago’s iconic hilltop park and the highest point in the capital, where views stretch from the urban sprawl to the snowcapped Andes. If you’re up for a little more movement, rent a bike or take a walk through the botanical gardens. For a quiet afternoon, stroll through one of Santiago’s trendiest neighborhoods, like Barrio Lastarria, whose cobbled streets and historic buildings reveal charming cafes and galleries. Grab a coffee, browse an exhibit, or people-watch from a sunny terrace.

Where to Eat & Drink

Dining at Boragó is less about eating, more about storytelling

Santiago’s culinary scene is booming, with a growing number of chefs and mixologists earning international recognition. At the forefront is Boragó, featured on the World’s 50 Best Restaurants list, where chef Rodolfo Guzmán’s tasting menus take diners on a storytelling journey through Chile’s diverse ecosystems, and feature native ingredients foraged from the mountains, coastline, and forests. For a memorable drink in Santiago, head to Bar La Providencia, which has also earned a place on 'The 50 Best' Discovery list. Chic yet cozy, the terrace here is a perfect spot for sipping one of many inventive cocktails, like the Penélope Glamour, crafted with blanco tequila and a splash of Italian aperitif. Back at the hotel, Matsuri also provides an exceptional dining experience and is an ideal spot to wind down after a day spent exploring. The omakase menu is a standout, cocktails well balanced (try the Pisco Sour) and sake pairings thoughtfully chosen. 

The Penélope Glamour at Bar La Providencia

Getting There & When to Visit

Traveling direct from Los Angeles to Santiago is a breeze thanks to LATAM Airlines non-stop service. Flight LA603 departs LAX in the mid-afternoon and, just under 11 hours later, lands at Santiago’s SCL early the next morning. Timing a visit depends on your plans beyond the city. During the Southern Hemisphere’s winter months (June through August), Santiago becomes a convenient gateway to nearby Andean ski resorts like Valle Nevado, making it a popular stop for winter sports enthusiasts. During Chile’s summer (December to February), many travelers use Santiago as a springboard for stargazing and outdoor adventures in the Atacama Desert.

Avenida Santa Isabel, Santiago credit: Gianni Donato/Unsplash

Keri Bridgwater

A native Brit, Keri Bridgwater spent time in house at magazines and publishers in Sweden, New Zealand and Telluride, Colorado before moving to San Diego over a decade ago. She specializes in travel stories, destination guides, hotel news, and profiles for various publications. Bylines in BBC Travel, Marie Claire, Forbes, Yoga Journal, and London's Evening Standard, among others. ...(Read More)